Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982021 | 1.00 | GLO1 (0.48) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL19525723 | 1.00 | GLO1 (0.48) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL30626325 | 1.00 | GLO1 (0.48) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL11872242 | 0.97 | GLO1 (0.47) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL9305761 | 0.97 | GLO1 (0.47) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL5322674 | 0.85 | SLC7A5 (0.44) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL2485256 | 0.85 | SLC7A5 (0.44) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL27927148 | 0.83 | SLC1A3 (0.39) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL11771843 | 0.81 | SLC1A3 (0.44) | GLO1SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL28051218 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984296-A | Thermally induced hydrogel embolic agent with X-ray developing capability and application thereof | 复旦大学 | 2022-09-02 | — | — | CN | disclosed |
| US-7592168-B2 | Cephalosporin C acylase mutant and method for preparing 7-ACA using same | SANDOZ AG (CH) | 2009-09-22 | — | — | US | disclosed |
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-3934027-A | 18β-Glycyrrhetinic acid amides useful as antiulcer agents | PFIZER INC. (US) | 1976-01-20 | — | — | US | disclosed |