Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 4/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245883 | 0.78 | GRM5 (0.49) | SYKBRAFTRPV1 | |
| SCHEMBL4898772 | 0.77 | SYK (0.39) | SYKSRCZAP70CYP1A1CYP1A2 | |
| SCHEMBL4902768 | 0.76 | RAB9A (0.39) | SYKSRCZAP70CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5360646 | 0.76 | BTK (0.38) | SYKSRCZAP70BRAFCYP1A1 | |
| Hydrochloric Acid SCHEMBL4904396 | 0.75 | RAB9A (0.39) | SYKSRCZAP70CYP1A1CYP1A2 | |
| SCHEMBL4899246 | 0.75 | RAB9A (0.48) | SYKSRCZAP70CYP1A1CYP1A2 | |
| SCHEMBL4903201 | 0.75 | RAB9A (0.42) | SYKSRCZAP70RAB9AECE1 | |
| Hydrochloric Acid SCHEMBL5309347 | 0.74 | RAB9A (0.47) | SYKSRCZAP70CYP1A1CYP1A2 | |
| SCHEMBL4891073 | 0.74 | CTSC (0.40) | SYKSRCZAP70CYP1A1CYP1A2 | |
| SCHEMBL4901213 | 0.73 | CTSC (0.47) | CDK2CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | SYK 4140/4885SRC 4155/4885ZAP70 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.