SCHEMBL490280

SCHEMBL490280

C=Nc1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16417243 0.88 ALDH1A1 (0.67)
SCHEMBL13771686 0.88 ALDH1A1 (0.67)
SCHEMBL15139208 0.88 ALDH1A1 (0.67)
Aniline SCHEMBL7809661 0.86 TSHR (0.58)
Pyridine SCHEMBL28299187 0.84 TSHR (0.45)
SCHEMBL5988861 0.82 ALDH1A1 (0.50)
SCHEMBL24591453 0.76 ALDH1A1 (0.62)
SCHEMBL6264315 0.73
Azobenzene SCHEMBL11878769 0.69 ALDH1A1 (1.00)
Azobenzene SCHEMBL6562161 0.69 ALDH1A1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590702-B Novel method for preparing 2-mercaptobenzothiazole 河南省化工研究所有限责任公司 2022-11-25 CN claimed
CN-113637166-B Toughened flame-retardant modified bismaleimide resin and application thereof 江南大学 2022-04-26 CN claimed
US-8350041-B2 Tricyclic δ-opioid modulators JANSSEN PHARMACEUTICA, NV (BE) 2013-01-08 US claimed
US-20120095010-A1 TRICYCLIC DELTA-OPIOID MODULATORS CARSON JOHN R (US) 2012-04-19 US claimed
US-8106207-B2 Tricyclic δ-opioid modulators JANSSEN PHARMACEUTICA, NV (BE) 2012-01-31 US claimed
JP-4810423-B2 2011-11-09 JP claimed
US-20110245291-A1 TRICYCLIC DELTA-OPIOID MODULATORS CARSON JOHN R 2011-10-06 US claimed
US-7982042-B2 delta-opioid receptor agonists as analgesics having reduced side effects and antagonists as immunosuppressants, antiinflammatory agents, neurological, psychiatric , urological and reproductive conditions;N-{2-[10-(8-Allyl-8-aza-bicyclo[3.2.1]oct-3-yl)-10H-phenothiazine-3-yl]-phenyl}-acetamide Janseen Pharmacautica NV (BE) 2011-07-19 US claimed
EP-1896467-B1 TRICYCLIC OPIOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2010-12-01 EP claimed
US-20100093709-A1 TRICYCLIC DELTA OPIOID MODULATORS COATS STEVEN J 2010-04-15 US claimed
US-4873116-A BLEND WITH MINERAL FILLER AND REINFORCEMENT ADDITIVE UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1989-10-10 US claimed
EP-0257828-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-02 EP claimed
EP-0073485-B1 REINFORCEMENT PROMOTERS FOR FILLED THERMOPLASTIC POLYMERS UNION CARBIDE CORPORATION (US) 1987-05-20 EP claimed
EP-0165904-A2 Substituted bicycle compounds CIBA-GEIGY AG (CH) 1985-12-27 EP claimed
US-RE31992-E AT LEAST TWO REACTIVE OLEFINC DOUBLE BONDS, PROVIDING BOTH IMPROVED TENSILE STRENGTH AND DUCTILITY UNION CARBIDE CORPORATION (US) 1985-09-24 US claimed
EP-0033183-B1 PHENYLIMINOMETHYL-3-PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-07-04 EP claimed
EP-0099329-A1 Dithio compounds, pharmaceutical preparations containing them and their use Zyma SA (CH) 1984-01-25 EP claimed
US-4385136-A Reinforcement promoters for filled thermoplastic polymers UNION CARBIDE CORPORATION (US) 1983-05-24 US claimed
EP-0013361-B1 SUBSTITUTED N-HALOGENOMETHYL ANILIDES, PROCESS FOR THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1981-09-16 EP claimed
EP-0013361-A2 Substituted N-halogenomethyl anilides, process for their preparation and use BASF Aktiengesellschaft (DE) 1980-07-23 EP claimed