SCHEMBL4902837

SCHEMBL4902837

CCCC[N+]12CCC(CC1)C(O)C2

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 3/20 0.49
APOBEC3G Q9HC16 3/20 0.49
RGS12 O14924 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CHKA P35790 1/20 0.39
HTT P42858 1/20 0.37
CHRM3 P20309 8/20 0.36
CHRM2 P08172 7/20 0.36
CHRM1 P11229 7/20 0.36
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
GLB1 P16278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6993749 0.93 APOBEC3A (0.47) APOBEC3AAPOBEC3GRGS12CYP2D6CYP2C9
Bromide SCHEMBL2816500 0.91 APOBEC3A (0.46) APOBEC3AAPOBEC3GRGS12CYP2D6CYP2C9
SCHEMBL4906359 0.88 CHKA (0.41) APOBEC3AAPOBEC3GRGS12CYP2D6CYP2C9
SCHEMBL4546743 0.86 CHKA (0.41) APOBEC3AAPOBEC3GRGS12CYP2D6CYP2C9
SCHEMBL4903052 0.79 CHKA (0.42) APOBEC3AAPOBEC3GCHKA
SCHEMBL4896649 0.78 CHKA (0.41) CHKA
SCHEMBL14860448 0.78 LMNA (0.39) APOBEC3AAPOBEC3GCHKACHRM3CHRM2
SCHEMBL14860804 0.76 LMNA (0.41) APOBEC3AAPOBEC3GCHKACHRM3CHRM2
Water SCHEMBL14863351 0.76 LMNA (0.38) APOBEC3AAPOBEC3GCHKACHRM3CHRM2
Bromide SCHEMBL14861641 0.76 LMNA (0.38) APOBEC3AAPOBEC3GRGS12CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867667-B1 Method for manufacturing stabilized polyacetal resin POLYPLASTICS CO (JP) 2012-10-31 EP disclosed
US-20080271381-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin POLYPLASTICS CO., LTD (JP) 2008-11-06 US disclosed
EP-1867667-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin Polyplastics Co., Ltd. (JP) 2007-12-19 EP disclosed