SCHEMBL4902896

SCHEMBL4902896

C=C(C)C(=O)Oc1ccc(CC#N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.50
KMT2A Q03164 5/20 0.48
ATM Q13315 1/20 0.47
PKM P14618 1/20 0.40
THRB P10828 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 1/20 0.37
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NR1H2 P55055 1/20 0.36
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.35
SLC22A12 Q96S37 1/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10033166 0.84 ELANE (0.48) ELANEKMT2AATMTHRBMEN1
SCHEMBL3932090 0.83 KMT2A (0.52) ELANEKMT2APKMMEN1ALDH1A1
SCHEMBL17791332 0.81 ELANE (0.57) ELANEKMT2AATMTHRBSMN1; SMN2
SCHEMBL2703931 0.81 ELANE (0.57) ELANEKMT2AATMTHRBMEN1
SCHEMBL56436 0.80 ELANE (0.69) ELANEKMT2AATMPKMRAB9A
SCHEMBL13260543 0.80 POLB (0.58) KMT2AMEN1ALDH1A1SMN1; SMN2HTT
SCHEMBL4594651 0.80 ELANE (0.56) ELANEKMT2AATMTHRBNPC1
SCHEMBL15814270 0.80 ELANE (0.56) ELANEKMT2AATMTHRBRAB9A
SCHEMBL4353041 0.80 ELANE (0.56) ELANEKMT2AATMTHRBMEN1
SCHEMBL10899629 0.79 HSD17B10 (0.53) ELANEKMT2APKMMEN1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128025-A1 BLOCK-COPOLYMER-CONTAINING EPOXY- BASED ADHESIVE COMPOSITION, PRODUCTION METHOD THEREFOR, AND CURED OBJECT OF BLOCK-COPOLYMER-CONTAINING EPOXY-BASED ADHESIVE アイシン化工株式会社 2024-06-20 WO disclosed
WO-2023094549-A1 FLEXIBLE PRESSURE-SENSITIVE ADHESIVES HAVING IMPROVED PROPERTIES WESTFÄLISCHE HOCHSCHULE GELSENKIRCHEN BOCHOLT RECKLINGHAUSEN (DE) 2023-06-01 WO disclosed
US-10889146-B2 Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-01-12 US disclosed
US-10829580-B2 Noncovalent soft elastomer and method for manufacturing the same NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) 2020-11-10 US disclosed
US-20190077899-A1 NONCOVALENT SOFT ELASTOMER AND METHOD FOR MANUFACTURING THE SAME NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2019-03-14 US disclosed
EP-2927253-B1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORP (JP) 2018-09-12 EP disclosed
US-10030131-B2 Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-24 US disclosed
EP-3296358-A1 NON-COVALENT BONDING SOFT ELASTOMER AND PRODUCTION PROCESS THEREFOR National University Corporation Nagoya University (JP) 2018-03-21 EP disclosed
US-9914328-B2 Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) 2018-03-13 US disclosed
US-20180043734-A1 TIRE OBJECT PROVIDED WITH AN ELASTOMER LAYER MADE OF A THERMOPLASTIC ELASTOMER IN THE FORM OF AN (A-B-(A-METHYLSTYRENE-CO-B))N-B-C BLOCK COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-02-15 US disclosed
US-20080233416-A1 PASTE COMPOSITION, GREEN CERAMIC BODY, AND METHODS FOR MANUFACTURING CERAMIC STRUCTURE KYOCERA CORPORATION (JP) 2008-09-25 US disclosed
US-20080044763-A1 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION 2008-02-21 US disclosed
US-20080044763-A1 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION 2008-02-21 US disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed