Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899629 | 0.95 | HSD17B10 (0.53) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL7773803 | 0.83 | LMNA (0.53) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL4902896 | 0.83 | ELANE (0.50) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL28267569 | 0.81 | KMT2A (0.52) | KMT2ALMNAMAPTPKMELANE | |
| SCHEMBL10402897 | 0.81 | LMNA (0.52) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL5169132 | 0.79 | LMNA (0.48) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL10897448 | 0.78 | KMT2A (0.50) | KMT2ALMNAMAPTPKMELANE | |
| SCHEMBL9081470 | 0.78 | LMNA (0.61) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL777803 | 0.78 | ELANE (0.62) | KMT2ALMNAMAPTPOLBPKM | |
| SCHEMBL269329 | 0.77 | LMNA (0.80) | KMT2ALMNAMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974730-A | Method for synthesizing organic sulfate by persulfate | 湖南大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-107011213-B | Multi-channel luminous fluorescent probe and preparation method and application thereof | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-2035366-A1 | PROCESS FOR PREPARATION OF 0-DESMETHYLVENLAFAXINE AND ITS ANALOGUES | KRKA (SI) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007147564-A1 | PROCESS FOR PREPARATION OF 0-DESMETHYLVENLAFAXINE AND ITS ANALOGUES | KRKA (SI) | 2007-12-27 | — | — | WO | disclosed |
| US-5892048-A | INSECTICIDES, MITICIDES | NIPPON SODA CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0717039-A1 | NOVEL TRIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-4335119-A | Quick-acting diuretic compositions | ROHM, PHARMA GMBH (DE) | 1982-06-15 | — | — | US | disclosed |
| US-4252809-A | DIURETICS | ROHM PHARMA GMBH (DE) | 1981-02-24 | — | — | US | disclosed |
| US-3984559-A | Compositions comprising tetramic acid analogs of pulvinic acid and methods of combating arthritis | SMITHKLINE CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |
| US-3947580-A | Anti-arthritic compositions comprising N-heterocyclic pulvinic acid amides and methods of producing anti-arthritic activity | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
| US-3931207-A | ANTIARTHRITIC | SMITHKLINE CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |