Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.64 |
| ▸ | BACE1 | P56817 | 7/20 | 0.64 |
| ▸ | BCHE | P06276 | 4/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634965 | 0.92 | BCHE (0.66) | ACHEBACE1BCHE | |
| SCHEMBL8408493 | 0.90 | ACHE (0.69) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL24770749 | 0.87 | SLC6A2 (0.59) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL7693701 | 0.85 | ACHE (0.68) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL10058198 | 0.85 | SLC6A2 (0.60) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL5723548 | 0.84 | ACHE (0.66) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL3473102 | 0.84 | ACHE (0.66) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL2498286 | 0.83 | ACHE (0.73) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL3474512 | 0.83 | ACHE (0.64) | ACHEBACE1BCHESLC6A2SLC6A4 | |
| SCHEMBL7467264 | 0.82 | ACHE (0.71) | ACHEBACE1BCHESLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |
| EP-1179341-B1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| EP-1553085-A1 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-1535909-A2 | Cyclic amine derivatives and their use as drugs | TEIJIN LIMITED (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6451842-B1 | Cyclic amine derivatives and their use as drugs | DUPONT PHARMACEUTICALS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-6410566-B1 | ATHEROSCLEROSIS; ANTIARTHRITIC AGENTS | TEIJIN LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6362177-B1 | INHIBITION OF CHEMOKINE BINDING | TEIJIN LIMITED (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1179341-A1 | REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES | TEIJIN LIMITED (JP) | 2002-02-13 | — | — | EP | disclosed |