Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663189 | 0.82 | PDPK1 (0.47) | HSP90AA1RAB9AADORA2AADORA1MAP4K4 | |
| SCHEMBL4902877 | 0.82 | RAB9A (0.61) | HSP90AA1RAB9AMETAP1SYKCDK2 | |
| Bromide SCHEMBL16340075 | 0.80 | PDPK1 (0.46) | HSP90AA1RAB9AADORA2AADORA1MAP4K4 | |
| SCHEMBL16159636 | 0.78 | RAB9A (0.54) | HSP90AA1RAB9AADORA2AADORA1METAP1 | |
| SCHEMBL2730329 | 0.77 | RAB9A (0.53) | HSP90AA1RAB9AMETAP1SYKCDK2 | |
| SCHEMBL16159715 | 0.76 | RAB9A (0.53) | HSP90AA1RAB9AADORA2AADORA1METAP1 | |
| SCHEMBL29290789 | 0.73 | HSP90AA1 (0.55) | HSP90AA1RAB9ASYKCDK2SRC | |
| SCHEMBL16159733 | 0.73 | RAB9A (0.49) | HSP90AA1RAB9AMETAP1SYKCDK2 | |
| SCHEMBL23888704 | 0.72 | CCR1 (0.52) | MAP4K4CYP2A6 | |
| SCHEMBL16159711 | 0.71 | RAB9A (0.54) | HSP90AA1RAB9AADORA2AADORA1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | HSP90AA1 3995/4885RAB9A 3132/4885ADORA2A 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.