Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.78 |
| ▸ | AR | P10275 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906635 | 1.00 | PGR (0.78) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4907750 | 0.91 | PGR (0.65) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4906858 | 0.91 | PGR (0.65) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4595879 | 0.91 | PGR (0.76) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4595878 | 0.91 | PGR (0.76) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4912021 | 0.89 | AR (0.73) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4904244 | 0.89 | PGR (0.73) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4904238 | 0.89 | PGR (0.73) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4912029 | 0.89 | AR (0.73) | PGRARCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4595648 | 0.89 | PGR (0.62) | PGRARCYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | claimed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | EDNRA, CYP19A1, HSD17B11 | PGR 64/4885AR 84/4885CYP2C19 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.