Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904536 | 0.98 | POLB (0.46) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL27986751 | 0.93 | TSHR (0.47) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL12975021 | 0.92 | POLB (0.50) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL16021261 | 0.92 | POLB (0.50) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL17788701 | 0.92 | POLB (0.50) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL12975236 | 0.90 | POLB (0.49) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 | |
| SCHEMBL29004671 | 0.87 | TSHR (0.44) | TSHRSMN1; SMN2POLBPOLA1CA12 | |
| SCHEMBL13443169 | 0.85 | TSHR (0.54) | TSHRSMN1; SMN2POLBPOLA1PPARG | |
| SCHEMBL12974997 | 0.83 | L3MBTL1 (0.47) | TSHRSMN1; SMN2POLBPOLA1PPARG | |
| SCHEMBL28996869 | 0.83 | ZDHHC7 (0.46) | TSHRSMN1; SMN2POLBPOLA1ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440608-B2 | Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof | V. MANE FILS (FR) | 2013-05-14 | — | — | US | disclosed |
| US-20080032914-A1 | Beta-Substituted Tetrahdropyrana (On) S And Method For The Synthesis And The Use Thereof | V. MANE FILS (FR) | 2008-02-07 | — | — | US | disclosed |