Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904881 | 1.00 | PGR (0.69) | PGRARCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4904251 | 0.88 | PGR (0.81) | PGRARCYP2C19 | |
| SCHEMBL4904248 | 0.88 | PGR (0.81) | PGRARCYP2C19 | |
| SCHEMBL4898472 | 0.83 | PGR (0.72) | PGRARCYP2C19 | |
| SCHEMBL4898474 | 0.83 | PGR (0.72) | PGRARCYP2C19 | |
| SCHEMBL4896095 | 0.82 | PGR (1.00) | PGRARCYP2C19 | |
| SCHEMBL4896105 | 0.82 | PGR (1.00) | PGRARCYP2C19 | |
| SCHEMBL4595785 | 0.74 | AR (0.74) | PGRARCYP2D6CYP2C9 | |
| SCHEMBL4595784 | 0.74 | AR (0.74) | PGRARCYP2D6CYP2C9 | |
| SCHEMBL4596260 | 0.73 | PGR (0.83) | PGRARCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | claimed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | EDNRA, CYP19A1, HSD17B11 | PGR 64/4885AR 84/4885CYP2D6 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.