Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608943 | 0.89 | HTT (0.70) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL18638757 | 0.86 | HTT (0.71) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL147291 | 0.84 | HTT (0.73) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL31185236 | 0.84 | HTT (0.68) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL29279417 | 0.84 | HTT (0.68) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL16981649 | 0.82 | HTT (0.66) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL8930726 | 0.81 | HTT (0.64) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL13255722 | 0.81 | HTT (0.64) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL18877602 | 0.80 | MTNR1B (0.61) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL16752846 | 0.80 | MTNR1B (0.59) | HTTRAB9ASMN1; SMN2NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | claimed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | claimed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | claimed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | NQO2, CBR3, COX4I1 | HTT 2702/4885RAB9A 3591/4885SMN1; SMN2 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.