⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11527267 | 0.98 | TDP1 (0.70) | — | |
| 4-Methylhistamine SCHEMBL9456351 | 0.80 | TDP1 (1.00) | — | |
| SCHEMBL9867663 | 0.79 | HRH1 (0.78) | — | |
| SCHEMBL2830891 | 0.78 | — | — | |
| SCHEMBL10855808 | 0.77 | HRH1 (0.75) | — | |
| SCHEMBL8014968 | 0.76 | — | — | |
| SCHEMBL10376001 | 0.76 | — | — | |
| SCHEMBL5791428 | 0.76 | — | — | |
| SCHEMBL9436244 | 0.76 | — | — | |
| SCHEMBL10964788 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101185882-A | High-capacity dewatering electric charge inducing color chromatogram medium and preparation method | UNIV TIANJIN (CN) | 2008-05-28 | — | — | CN | claimed |
| US-20250059220-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-02-20 | — | — | US | disclosed |
| WO-2023121939-A1 | SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| CN-106281164-A | A kind of heat-resistant fireproof electron pouring sealant and preparation method thereof | 王泽陆 | 2017-01-04 | — | — | CN | disclosed |
| US-7462625-B2 | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| CN-101185882-A | High-capacity dewatering electric charge inducing color chromatogram medium and preparation method | UNIV TIANJIN (CN) | 2008-05-28 | — | — | CN | disclosed |
| US-20080051578-A1 | SUBSTITUTED BIARYLS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF AS MEDICAMENTS | DAHMANN GEORG | 2008-02-28 | — | — | US | disclosed |
| US-20070208049-A1 | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-4267337-A | Imidazolemethylphosphonium salts | SK&F LAB CO. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4215217-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4119781-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1978-10-10 | — | — | US | disclosed |