Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 11/20 | 0.58 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | NEK4 | P51957 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781984 | 0.90 | PLK1 (0.56) | PLK1PLK3ALKBRD4LRRK2 | |
| SCHEMBL14221013 | 0.88 | PLK1 (0.54) | PLK1PLK3ALKBRD4PLK2 | |
| SCHEMBL4783604 | 0.86 | PLK1 (0.68) | PLK1PLK3ALKBRD4DCLK1 | |
| SCHEMBL4784785 | 0.86 | PLK1 (0.61) | PLK1PLK3ALKBRD4DCLK1 | |
| SCHEMBL4780676 | 0.85 | PLK1 (0.54) | PLK1PLK3ALKBRD4PLK2 | |
| SCHEMBL14220959 | 0.85 | PLK1 (0.64) | PLK1PLK3ALKBRD4PLK2 | |
| SCHEMBL14220957 | 0.85 | PLK1 (0.64) | PLK1PLK3ALKBRD4PLK2 | |
| SCHEMBL4846259 | 0.84 | PLK1 (0.58) | PLK1PLK3ALKBRD4DCLK1 | |
| SCHEMBL4782392 | 0.84 | PLK1 (0.62) | PLK1PLK3ALKBRD4DCLK1 | |
| SCHEMBL4780616 | 0.83 | PLK1 (0.65) | PLK1PLK3ALKBRD4DCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040951-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2008-04-10 | — | — | WO | disclosed |