Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.55 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cotinine SCHEMBL5574865 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL30478620 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL29404962 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL49060 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL9067899 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL29450216 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL10899074 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL1615810 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL1615812 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL4659033 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8247 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117735596-B | Preparation method of nano zinc sulfide composite material | SHANXI KUNMING TOBACCO CO.,LTD. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119165094-B | Method for detecting psychotropic narcotics in environmental sludge based on acidic condition pretreatment and application | 浙江省化工产品质量检验站有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122016988-A | Simultaneous detection method for nicotine, metabolites, neurotransmitters and lipids in brain tissue sample | 国家烟草质量监督检验中心 | 2026-05-12 | — | — | CN | claimed |
| EP-4482527-B1 | CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2026-04-08 | — | — | EP | claimed |
| EP-4720665-A1 | METHOD OF DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE | Molecular You Corporation (CA) | 2026-04-08 | — | — | EP | claimed |
| US-20260086100-A1 | Method of Determining Risk for Chronic Stress and Stroke | UNIV NORTHWEST (ZA) | 2026-03-26 | — | — | US | claimed |
| EP-4007921-B1 | METHOD OF DETERMINING RISK FOR CHRONIC STRESS AND STROKE | UNIV NORTHWEST (ZA) | 2026-03-25 | — | — | EP | claimed |
| US-20260053182-A1 | USE OF PECTIN OR OTHER ANIONIC POLYMERS IN THE STABILIZATION AND CONTROLLED RELEASE OF NICOTINE IN ORAL SENSORIAL TOBACCO PRODUCTS OR NICOTINE CONTAINING NON-TOBACCO ORAL SENSORIAL PRODUCTS | ALTRIA CLIENT SERVICES LLC (US) | 2026-02-26 | — | — | US | claimed |
| EP-4698229-A1 | BISPECIFIC CYTOTOXICITY TARGETING CHIMERAS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2026-02-25 | — | — | EP | claimed |
| EP-4698225-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR ANTIBODY-DRUG CONJUGATES AND BISPECIFIC ANTIBODIES | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2026-02-25 | — | — | EP | claimed |
| WO-1993003367-A1 | DIFFERENTIAL BINDING AFFINITIES AND DISSOCIATION ASSAYS BASED THEREON | SEREX, INC. (US) | 1993-02-18 | — | — | WO | claimed |
| US-5187169-A | Cotidine derivatives; Addison's and Parkinson's disease; 3-(1-alkyl-5-oxoindol-2-yl)pyridines; antidepressants; cholinergic agents | R. J. REYNOLDS TOBACCO COMPANY (US) | 1993-02-16 | — | — | US | claimed |
| EP-0516746-A1 | ORAL COLLECTION FOR IMMUNOASSAY. | EPITOPE INC (US) | 1992-12-09 | — | — | EP | claimed |
| WO-1992018868-A1 | CROSSTALK INHIBITORS AND THEIR USES | BIOSITE DIAGNOSTICS INCORPORATED (US) | 1992-10-29 | — | — | WO | claimed |
| WO-1992012975-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR IMMUNOASSAYS FOR COTININE | ABBOTT LABORATORIES (US) | 1992-08-06 | — | — | WO | claimed |
| US-5103836-A | Absorbing saliva in pad impregnated with hypertonic solution; screening tool for diseases | EPITOPE, INC. (US) | 1992-04-14 | — | — | US | claimed |
| WO-1991013355-A2 | ORAL COLLECTION FOR IMMUNOASSAY | EPITOPE, INC. (US) | 1991-09-05 | — | — | WO | claimed |
| EP-0194158-A2 | Anti-nicotine and anti-cotinine antibodies (monoclonal and other), and their uses in nicotine and cotinine assays | Baylor College of Medicine (US) | 1986-09-10 | — | — | EP | claimed |
| US-4590278-A | COTININE, INSECTICIDES | PHILIP MORRIS INCORPORATED (US) | 1986-05-20 | — | — | US | claimed |
| US-4332945-A | DERIVATIVES OF COTININE | PHILIP MORRIS, INCORPORATED (US) | 1982-06-01 | — | — | US | claimed |