Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.55 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cotinine SCHEMBL30478620 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL29404962 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL49061 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL49060 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL9067899 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL29450216 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL10899074 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL1615810 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL1615812 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO | |
| Cotinine SCHEMBL4659033 | 0.98 | KDM4E (0.97) | KDM4ECYP3A4THRBTSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1857121-A2 | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same | Xenova Research Limited (GB) | 2007-11-21 | — | — | EP | disclosed |
| EP-1024834-A2 | HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME | IMMULOGIC PHARMACEUTICAL CORPORATION (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1998014216-A9 | HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME | — | 1998-08-13 | — | — | WO | disclosed |
| WO-1998014216-A2 | HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME | IMMULOGIC PHARMACEUTICAL CORPORATION (US) | 1998-04-09 | — | — | WO | disclosed |