Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893867 | 0.84 | APOBEC3A (0.39) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL868069 | 0.80 | GNAI3 (0.41) | CHRNA7 | |
| SCHEMBL2525998 | 0.80 | GNAI3 (0.41) | CHRNA7 | |
| Water SCHEMBL2526562 | 0.79 | GNAI3 (0.40) | CHRNA7 | |
| Iodide SCHEMBL3854066 | 0.79 | GNAI3 (0.40) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Bromide SCHEMBL2524389 | 0.79 | GNAI3 (0.40) | CHRNA7BCHEACHE | |
| SCHEMBL4902669 | 0.77 | CHRNA7 (0.45) | CHRNA7LMNABCHEACHECHKA | |
| SCHEMBL12638606 | 0.74 | CHRNA7 (0.36) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Bromide SCHEMBL7629729 | 0.74 | CHRNA7 (0.36) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1666073 | 0.74 | CHRNA7 (0.36) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110087729-B | Bifunctional compound with quaternary ammonium salt structure | 北京硕佰医药科技有限责任公司 | 2022-04-05 | — | — | CN | claimed |
| CN-110087729-B | Bifunctional compound with quaternary ammonium salt structure | 北京硕佰医药科技有限责任公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3556435-A1 | CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE | Beijing Showby Pharmaceutical Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |
| EP-3248982-A1 | THIOSULFONATE REAGENTS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS | Wave Life Sciences Ltd. (SG) | 2017-11-29 | — | — | EP | disclosed |
| US-9605019-B2 | Methods for the synthesis of functionalized nucleic acids | WAVE LIFE SCIENCES LTD. (SG) | 2017-03-28 | — | — | US | disclosed |
| EP-2734208-B1 | METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS | WAVE LIFE SCIENCES LTD (SG) | 2017-03-01 | — | — | EP | disclosed |
| US-20170037399-A1 | CHIRAL DESIGN | WAVE LIFE SCIENCES LTD. (SG) | 2017-02-09 | — | — | US | disclosed |
| WO-2013012758-A1 | METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS | ONTORII, INC. (US) | 2013-01-24 | — | — | WO | disclosed |
| EP-1867667-B1 | Method for manufacturing stabilized polyacetal resin | POLYPLASTICS CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2008142560-A2 | METHOD FOR THE PRODUCTION OF BINARY CLATHRATE HYDRATES OF HYDROGEN | ARCA SIMONE (IT) | 2008-11-27 | — | — | WO | disclosed |
| US-20080271381-A1 | Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin | POLYPLASTICS CO., LTD (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1867667-A1 | Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin | Polyplastics Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |