SCHEMBL4906593

SCHEMBL4906593

C=Cc1ccc(C(=O)OCCN(C)C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.65
ALDH1A1 P00352 3/20 0.58
MAPT P10636 1/20 0.58
GAA P10253 1/20 0.54
LMNA P02545 3/20 0.53
MAOA P21397 2/20 0.53
HRH3 Q9Y5N1 2/20 0.53
SCN1A P35498 2/20 0.53
SCN2A Q99250 2/20 0.53
SCN3A Q9NY46 2/20 0.53
CYP1A2 P05177 1/20 0.53
CNR1 P21554 1/20 0.53
DRD4 P21917 1/20 0.53
ACHE P22303 1/20 0.53
HRH2 P25021 1/20 0.53
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
MAPK1 P28482 1/20 0.53
NTSR1 P30989 1/20 0.53
HRH1 P35367 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11677667 0.98 PHLPP2 (0.63) PHLPP2ALDH1A1MAPTGAALMNA
SCHEMBL8963488 0.87 PHLPP2 (0.83) PHLPP2ALDH1A1MAPTGAALMNA
SCHEMBL16795363 0.86 PHLPP2 (0.67) PHLPP2ALDH1A1MAPTGAALMNA
SCHEMBL4903510 0.85 TSHR (0.67) PHLPP2ALDH1A1MAPTLMNAMAOA
SCHEMBL26417020 0.85 SNCA (0.49) PHLPP2ALDH1A1MAPTLMNACYP1A2
Hydrochloric Acid SCHEMBL11680444 0.84 BLM (0.68) ALDH1A1MAPTLMNAMAOAHRH3
SCHEMBL11683280 0.84 PHLPP2 (0.46) PHLPP2ALDH1A1MAPTGAALMNA
Hydrochloric Acid SCHEMBL11679451 0.82 BLM (0.45) PHLPP2ALDH1A1MAPTGAALMNA
SCHEMBL8487897 0.82 PHLPP2 (0.71) PHLPP2ALDH1A1MAPTGAALMNA
SCHEMBL4904335 0.82 ALDH1A1 (0.64) ALDH1A1MAPTLMNACYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4004025-A Long-acting local subcutaneously-applied anesthetics and compositions containing the same Lewenstein, Evalina (US) 1977-01-18 US claimed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8389185-B2 Pigment dispersion, colored curable composition, color filter and method of manufacturing the same FUJIFILM CORPORATION (JP) 2013-03-05 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20110045412-A1 PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0907666-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-14 EP disclosed
WO-1997049736-A2 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed