⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325547 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL8021110 | 0.79 | CYP3A4 (0.35) | — | |
| SCHEMBL11677324 | 0.78 | TSHR (0.34) | — | |
| SCHEMBL10475870 | 0.78 | HCAR2 (0.42) | — | |
| SCHEMBL10475871 | 0.78 | HCAR2 (0.42) | — | |
| SCHEMBL7165889 | 0.78 | MAPT (0.39) | — | |
| SCHEMBL8636431 | 0.77 | — | — | |
| SCHEMBL5493232 | 0.77 | — | — | |
| SCHEMBL599364 | 0.77 | — | — | |
| SCHEMBL8442648 | 0.76 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2572733-A1 | Polymer-factor VIII moiety conjugates | Nektar Therapeutics (US) | 2013-03-27 | — | — | EP | claimed |
| US-7364599-B2 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-04-29 | — | — | US | claimed |
| WO-2005087902-A1 | METHODS FOR INCREASED REMOVAL OF DRAG REDUCER ADDITIVES FROM LIQUID HYDROCARBON FUEL | SOUTHWEST RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | WO | claimed |
| US-20040249233-A1 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE | 2004-12-09 | — | — | US | claimed |
| US-8808681-B2 | Crosslinked, degradable polymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080145338-A1 | Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-06-19 | — | — | US | disclosed |
| US-7364599-B2 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-04-29 | — | — | US | disclosed |
| US-20040249233-A1 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE | 2004-12-09 | — | — | US | disclosed |