Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920830 | 0.87 | CYP3A4 (0.41) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9718507 | 0.87 | — | — | |
| SCHEMBL1920831 | 0.84 | CYP3A4 (0.33) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL5918259 | 0.84 | CYP3A4 (0.31) | CYP3A4 | |
| SCHEMBL3806433 | 0.82 | CYP3A4 (0.37) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL8026690 | 0.82 | ALDH1A1 (0.48) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL599364 | 0.81 | — | — | |
| SCHEMBL6936082 | 0.80 | HDAC6 (0.33) | TSHR | |
| SCHEMBL6536969 | 0.79 | — | — | |
| SCHEMBL555029 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156889-A | Reagent useful for cleaving a protected functional group | RHODIA CHIMIE (FR) | 2000-12-05 | — | — | US | disclosed |