Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.54 |
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906861 | 1.00 | AR (0.54) | ARPGRS1PR1UBE2MDCUN1D1 | |
| SCHEMBL4906346 | 0.86 | AR (0.62) | ARPGRS1PR1UBE2MDCUN1D1 | |
| SCHEMBL4903938 | 0.81 | AR (0.63) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4903942 | 0.81 | AR (0.63) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4596174 | 0.80 | PGR (0.61) | ARPGRS1PR1 | |
| SCHEMBL4596170 | 0.80 | PGR (0.61) | ARPGRS1PR1 | |
| SCHEMBL4905911 | 0.80 | AR (0.60) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4904392 | 0.80 | AR (0.60) | ARPGRS1PR1RXRARXRB | |
| SCHEMBL4904299 | 0.78 | PGR (0.61) | ARPGR | |
| SCHEMBL4904305 | 0.78 | PGR (0.61) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | claimed |
| US-20080194536-A1 | Cyanoarylamines | SMITHKLINE BEECHAM CORPORATION | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194536-A1 | Cyanoarylamines | EDNRA, CYP19A1, HSD17B11 | AR 84/4885PGR 64/4885S1PR1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.