SCHEMBL4906892

SCHEMBL4906892

COCCN1CC[N+](C)(CCOC)CC1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
HSD11B1 P28845 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
ALDH1A1 P00352 1/20 0.32
GBA1 P04062 1/20 0.32
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29343389 0.88 KDM4E (0.46) KDM4ECHRM2CHRM4CHRM5CHRM1
SCHEMBL4904967 0.83 KDM4E (0.57) KDM4E
SCHEMBL4898214 0.78 KDM4E (0.73) KDM4ECHRM3
SCHEMBL18084202 0.78
SCHEMBL4893229 0.77 CHRM2 (0.35) KDM4ECHRM2CHRM4CHRM5CHRM1
SCHEMBL4893194 0.75 HSD11B1 (0.47) KDM4EHSD11B1ALDH1A1GBA1KDM1A
SCHEMBL8149011 0.75 HSD11B1 (0.47) KDM4EHSD11B1ALDH1A1GBA1KDM1A
SCHEMBL6057032 0.75
SCHEMBL23484985 0.73
SCHEMBL372602 0.73 KDM4E (0.91) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867667-B1 Method for manufacturing stabilized polyacetal resin POLYPLASTICS CO (JP) 2012-10-31 EP disclosed
US-20080271381-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin POLYPLASTICS CO., LTD (JP) 2008-11-06 US disclosed
EP-1867667-A1 Method for manufacturing stabilized polyacetal resin, stabilized polyacetal resin, stabilized polyacetal resin composition, and molded article of stabilized polyacetal resin Polyplastics Co., Ltd. (JP) 2007-12-19 EP disclosed