SCHEMBL490729

SCHEMBL490729

O=C(O)[CH]CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9862076 0.97 ALDH1A1 (0.50)
SCHEMBL28023144 0.97
SCHEMBL27694194 0.97 ALDH1A1 (0.50)
SCHEMBL5694524 0.73
SCHEMBL1388110 0.73
SCHEMBL3511034 0.73
SCHEMBL4368042 0.73 ALDH1A1 (0.47)
SCHEMBL27804356 0.73
SCHEMBL7094052 0.73
SCHEMBL753574 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3334710-B1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-10-04 EP claimed
WO-2023131655-A1 ONE-COMPONENT MOISTURE CURING COMPOSITION SIKA TECHNOLOGY AG (CH) 2023-07-13 WO claimed
US-20230133465-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2023-05-04 US claimed
CN-115943307-A MR1 ligands and pharmaceutical compositions for immunomodulation 巴塞尔大学 2023-04-07 CN claimed
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2023-03-30 US claimed
EP-3889602-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION Universität Basel (CH) 2021-10-06 EP claimed
US-10590070-B2 Compositions and methods for treating and preventing neurodegenerative disorders ALZHEON, INC. (US) 2020-03-17 US claimed
US-10202486-B2 Poly(oxyalkylene)urethanes as a solubilizer and stabilizer in active ingredient formulations BASF SE (DE) 2019-02-12 US claimed
EP-3334710-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING NEURODEGENERATIVE DISORDERS Alzheon, Inc. (US) 2018-06-20 EP claimed
CN-107632002-A A kind of composite fluorescence biology sensor and its production and use 北京理工大学 2018-01-26 CN claimed
WO-1991009036-A1 BETA-LACTAM DERIVATIVES FARMITALIA CARLO ERBA S.R.L. (IT) 1991-06-27 WO claimed
EP-0277671-B1 PLASTISOLS BASED ON POLYMERS OF VINYL CHLORIDE, AND THE USE OF THESE PLASTISOLS IN THE COATING OF CATAPHORETICALLY TREATED PLATES SOLVAY & Cie (Société Anonyme) (BE) 1991-05-08 EP claimed
US-4790856-A SYNERGISTIC COLGATE-PALMOLIVE COMPANY (US) 1988-12-13 US claimed
US-4766133-A ANTIULCER AGENTS HOFFMAN-LA ROCHE INC. (US) 1988-08-23 US claimed
EP-0214479-A2 Benzimidazol-2-ylpyridinium compounds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1987-03-18 EP claimed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP claimed
EP-0000930-B1 N-CARBOXYALKANE-AMINOALKANE-DIPHOSPHONIC ACIDS, N-CARBOXYALKANE-AZACYCLOALKANE-DIPHOSPHONIC ACIDS AND N-CARBOXYALKANE-AMINOARYLKANE DIPHOSPHONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SEQUESTERING AGENTS Benckiser-Knapsack GmbH (DE) 1981-07-01 EP claimed
US-4111804-A CARBOXYLATED SULFOXIDES OR SULFONES CIBA-GEIGY CORPORATION (US) 1978-09-05 US claimed
US-4010038-A COMPLEX HYDROPHILIC COLLOID ENCLOSING FINE PARTICLES OF HYDROPHOBIC SUBSTANCE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1977-03-01 US claimed
US-3984569-A Cosmetic compositions for treating the hair containing S-substituted derivatives of glutathione L'OREAL (FR) 1976-10-05 US claimed