SCHEMBL4907333

SCHEMBL4907333

C=C(CC[P+](C)(C)C)C(=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.41
BBOX1 O75936 1/20 0.35
CA2 P00918 1/20 0.32
CYP3A4 P08684 2/20 0.31
TSHR P16473 2/20 0.31
NFKB1 P19838 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL5058992 0.73 CA1 (0.34) CA1BBOX1CYP3A4TSHRNFKB1
Potassium Ion SCHEMBL20262527 0.72
SCHEMBL5052485 0.71 CA1 (0.36) CA1CA2CYP3A4TSHRNFKB1
SCHEMBL2541608 0.70 HDAC3 (0.50) CA1TSHR
Zinc Ion SCHEMBL18204918 0.70 HDAC3 (0.50) CA1TSHR
SCHEMBL18204914 0.70 HDAC3 (0.50) CA1TSHR
SCHEMBL18204910 0.70 HDAC3 (0.50) CA1TSHR
SCHEMBL5692777 0.70 HDAC3 (0.50) CA1TSHR
SCHEMBL18315393 0.70 HDAC3 (0.50) CA1TSHR
Lithium Ion SCHEMBL18315396 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080193497-A1 Hydrophilic Coating of a Water-Swellable Hydrophilic Matrix and an Anti-Microbial Polymer COLOPLAST A/S (DK) 2008-08-14 US disclosed
US-20080125513-A1 Hydrophilic, Water-Swellable, Cross-Linked Matrix Having Incorporated Therein an Anti-Microbial Polymer COLOPLAST A/S (DK) 2008-05-29 US disclosed
EP-1773421-A1 A HYDROPHILIC, WATER-SWELLABLE, CROSS-LINKED MATRIX HAVING INCORPORATED THEREIN AN ANTI-MICROBIAL POLYMER COLOPLAST A/S (DK) 2007-04-18 EP disclosed
EP-1740044-A1 A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER COLOPLAST A/S (DK) 2007-01-10 EP disclosed
WO-2006002628-A1 A HYDROPHILIC, WATER-SWELLABLE, CROSS-LINKED MATRIX HAVING INCORPORATED THEREIN AN ANTI-MICROBIAL POLYMER COLOPLAST A/S (DK) 2006-01-12 WO disclosed
WO-2005104845-A1 A HYDROPHILIC COATING OF A WATER-SWELLABLE HYDROPHILIC MATRIX AND AN ANTI-MICROBIAL POLYMER COLOPLAST A/S (DK) 2005-11-10 WO disclosed