Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052485 | 0.98 | CA1 (0.36) | CA1CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL1877809 | 0.82 | GRIK1 (0.36) | — | |
| SCHEMBL1568418 | 0.81 | GABRP (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL5053946 | 0.81 | GRIK1 (0.35) | — | |
| SCHEMBL14761132 | 0.77 | CYP3A4 (0.34) | CA1CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL18222440 | 0.73 | — | — | |
| SCHEMBL4907333 | 0.73 | CA1 (0.41) | CA1BBOX1CYP3A4TSHRNFKB1 | |
| SCHEMBL27602590 | 0.73 | GABRP (0.56) | TSHRNFKB1 | |
| SCHEMBL2932894 | 0.72 | GRIK1 (0.34) | — | |
| SCHEMBL14955034 | 0.71 | TP53 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281014-A1 | Nanosubstance-Containing Composition, Process for Producing the Same, and Composite Made With the Same | MITSUBISHI RAYON CO., LTD. (JP) | 2008-11-13 | — | — | US | disclosed |