SCHEMBL4907360

SCHEMBL4907360

C=C(C)C(=O)OCC(C)(C)COOCC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 4/20 0.41
ALDH1A1 P00352 4/20 0.36
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SERPINE1 P05121 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15337 0.87 TSHR (0.50) THRBTSHRALDH1A1SERPINE1
SCHEMBL750628 0.86 TSHR (0.40) THRBTSHRALDH1A1SERPINE1
SCHEMBL18159068 0.84 TSHR (0.39) THRBTSHRALDH1A1SERPINE1
SCHEMBL9703968 0.84 TSHR (0.41) THRBTSHRALDH1A1SERPINE1
SCHEMBL1067041 0.84 THRB (0.56) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL28087702 0.84 TSHR (0.41) THRBTSHRALDH1A1SERPINE1
SCHEMBL8773894 0.81 THRB (0.57) THRBTSHRALDH1A1SERPINE1
SCHEMBL9576258 0.81 THRB (0.47) THRBTSHRALDH1A1SERPINE1
SCHEMBL11682314 0.81 TSHR (0.45) THRBTSHRALDH1A1LMNAHSD17B10
Methacrylic Acid SCHEMBL28241961 0.81 TSHR (0.45) THRBTSHRALDH1A1SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080233305-A1 Method for manufacturing coating film TOPPAN PRINTING CO., LTD. (JP) 2008-09-25 US disclosed