⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816 | 0.95 | — | — | |
| SCHEMBL5615809 | 0.90 | — | — | |
| SCHEMBL8030971 | 0.90 | — | — | |
| SCHEMBL19198171 | 0.90 | — | — | |
| Fluoride SCHEMBL7996422 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL11054970 | 0.90 | LAP3 (0.35) | — | |
| SCHEMBL8009121 | 0.90 | — | — | |
| SCHEMBL9504478 | 0.90 | LAP3 (0.35) | — | |
| Fluoride SCHEMBL5035771 | 0.90 | — | — | |
| Propane SCHEMBL5395474 | 0.90 | LAP3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070862-A1 | Methods using glycosaminoglycans for the treatment of nephropathy | LASTER MORRIS | 2008-03-20 | — | — | US | disclosed |
| US-20070173479-A1 | Methods Using Sulodexide for the Treatment of Bladder Disease | KERYX BIOPHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| EP-1392329-B1 | USE OF SULODEXIDE FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | KERYX BIOPHARMCEUTICALS INC (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20050209188-A1 | Oral administering of mucopolysaccharides; treatment of HIV-associated nephropathy; sulodexide | KERYX BIOPHARMACEUTICALS, INC. | 2005-09-22 | — | — | US | disclosed |
| EP-1406640-A2 | USE OF GLYCOSAMINOGLYCANS FOR THE TREATMENT OF HIV-ASSOCIATED NEPHROPATHY | Keryx Biopharmceuticals Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030013680-A1 | Methods using glycosaminoglycans for the treatment of nephropathy | KERYX | 2003-01-16 | — | — | US | disclosed |
| US-20030008844-A1 | Use of sulodexide for the treatment of inflammatory bowel disease | KERYX BIOPHARMACEUTICALS, INC. | 2003-01-09 | — | — | US | disclosed |
| WO-2002100417-A2 | USE OF GLYCOSAMINOGLYCANS FOR THE TREATMENT OF HIV-ASSOCIATED NEPHROPATHY | KERYX BIOPHARMACEUTICALS INC. (US) | 2002-12-19 | — | — | WO | disclosed |