Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | POLB | P06746 | 1/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.78 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.78 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.74 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | SCN1A | P35498 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benactyzine SCHEMBL4419579 | 0.98 | MEN1 (1.00) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Benactyzine SCHEMBL7799126 | 0.97 | MEN1 (0.92) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Benactyzine SCHEMBL5858474 | 0.94 | MEN1 (0.87) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Benapryzine SCHEMBL250007 | 0.93 | MEN1 (0.84) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Benapryzine SCHEMBL635131 | 0.92 | MEN1 (0.87) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL29758978 | 0.86 | KMT2A (0.72) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Aprofene SCHEMBL2354824 | 0.85 | CHRM2 (1.00) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL8134339 | 0.84 | CHRM1 (0.71) | MEN1KMT2APOLBCHRM2CHRM1 | |
| SCHEMBL29358808 | 0.84 | MEN1 (0.70) | MEN1KMT2APOLBCHRM2CHRM1 | |
| Aprofene SCHEMBL12481597 | 0.84 | CHRM2 (0.97) | MEN1KMT2APOLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2711 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629360-B2 | Ophthalmic composition | Sydnexis, Inc. (US) | 2026-05-19 | — | — | US | claimed |
| US-20250090545-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF PERIPHERAL NEUROPATHIES | UNIV MANITOBA (CA) | 2025-03-20 | — | — | US | claimed |
| EP-3706762-B1 | N4-HYDROXYCYTIDINE DERIVATIVE AND ANTI-VIRAL USES RELATED THERETO | UNIV EMORY (US) | 2024-10-16 | — | — | EP | claimed |
| US-20240165098-A1 | OPHTHALMIC COMPOSITION | Sydnexis, Inc. | 2024-05-23 | — | — | US | claimed |
| US-20240139166-A1 | OPHTHALMIC COMPOSITIONS FOR PRESBYOPIA | Sydnexis, Inc. | 2024-05-02 | — | — | US | claimed |
| EP-4360628-A2 | COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC EFFECTS | Antecip Bioventures II LLC (US) | 2024-05-01 | — | — | EP | claimed |
| US-11896588-B2 | Ophthalmic composition | Sydnexis, Inc. (US) | 2024-02-13 | — | — | US | claimed |
| US-11890277-B2 | Ophthalmic composition | Sydnexis, Inc. (US) | 2024-02-06 | — | — | US | claimed |
| US-11883390-B2 | Ophthalmic composition | Sydnexis, Inc. (US) | 2024-01-30 | — | — | US | claimed |
| EP-4288049-A1 | OPHTHALMIC COMPOSITIONS FOR PRESBYOPIA | Sydnexis, Inc. (US) | 2023-12-13 | — | — | EP | claimed |
| WO-1991015176-A1 | DEVICE AND METHOD FOR ENHANCED ADMINISTRATION OF PHYSOSTIGMINE | PHARMETRIX CORPORATION (US) | 1991-10-17 | — | — | WO | claimed |
| US-5039528-A | EAA antagonists as anti-emetic drugs | OLNEY JOHN W (US) | 1991-08-13 | — | — | US | claimed |
| US-5034400-A | N-methyl-D-aspartate antagonist for side effect reduction | OLNEY JOHN W (US) | 1991-07-23 | — | — | US | claimed |
| EP-0432994-A2 | Excitatory amino acid antagonists as anti-emetic drugs | Olney, John William (US) | 1991-06-19 | — | — | EP | claimed |
| US-5011853-A | Compounds for treatment of cholinergic neurotoxins | WASHINGTON UNIVERSITY (US) | 1991-04-30 | — | — | US | claimed |
| EP-0424179-A2 | Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration | Olney, John William (US) | 1991-04-24 | — | — | EP | claimed |
| EP-0414568-A2 | Use of anticholinergic compounds for protecting the central nervous system against cholinergic neurotoxins | WASHINGTON UNIVERSITY (US) | 1991-02-27 | — | — | EP | claimed |
| EP-0332826-A1 | Injectable pharmaceutical compositions having improved stability, and methods of producing the same | Teva Pharmaceutical Industries Limited (IL) | 1989-09-20 | — | — | EP | claimed |
| US-4788063-A | FATTY ACID, CHOLINERGIC OR ANTICHOLINERGIC AGENT | STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 1988-11-29 | — | — | US | claimed |
| US-4675326-A | MONO AND BIS-PYRIDINIUM OXIMES FOR ORGANOPHOSPHOROUS AND CARB AMATE POISONING | STATE OF ISRAEL, PRIME MINISTERS OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH | 1987-06-23 | — | — | US | claimed |