Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9047935 | 0.98 | POLB (0.74) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Benactyzine SCHEMBL49077 | 0.84 | MEN1 (0.97) | CHRM1CHRM2CHRM3POLBMEN1 | |
| SCHEMBL29468676 | 0.84 | CHRM2 (0.63) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Benactyzine SCHEMBL4419579 | 0.83 | MEN1 (1.00) | CHRM1CHRM2CHRM3POLBMEN1 | |
| SCHEMBL9569379 | 0.83 | ALDH1A1 (0.61) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Benactyzine SCHEMBL7799126 | 0.82 | MEN1 (0.92) | CHRM1CHRM2CHRM3POLBMEN1 | |
| SCHEMBL5158545 | 0.81 | MEN1 (0.68) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Hydrochloric Acid SCHEMBL9569376 | 0.81 | POLB (0.61) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Benapryzine SCHEMBL250007 | 0.81 | MEN1 (0.84) | CHRM1CHRM2CHRM3POLBMEN1 | |
| Benactyzine SCHEMBL5858474 | 0.80 | MEN1 (0.87) | CHRM1CHRM2CHRM3POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |
| EP-0537608-A2 | Process for the technical preparation of 2,2-diphenyl-2-(2-ethyl-butoxy)acetic acid, 2-dimethyl-amino-ethyl ester, hydrochloride | APOGEPHA ARZNEIMITTEL GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |