Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141310 | 0.88 | TSHR (0.41) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL733134 | 0.81 | TSHR (0.40) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL16203246 | 0.80 | TSHR (0.35) | TSHRALDH1A1ALOX15 | |
| SCHEMBL17669223 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1ABCC4MAPTLMNA | |
| Allyl Alcohol SCHEMBL28349785 | 0.76 | TSHR (0.56) | TSHR | |
| SCHEMBL18191764 | 0.76 | ALDH1A1 (0.36) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL25410498 | 0.75 | MAPT (0.39) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL30517291 | 0.75 | MAPT (0.39) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL4646715 | 0.75 | — | — | |
| SCHEMBL3123097 | 0.74 | TSHR (0.41) | TSHRALDH1A1ABCC4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446437-B1 | COMPOUNDS CONTAINING QUATERNARY CARBONS, MEDICAL DEVICES, AND METHODS | MEDTRONIC INC (US) | 2015-04-15 | — | — | EP | disclosed |
| US-20080064845-A9 | Compounds containing quaternary carbons, medical devices, and methods | MEDTRONIC, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-20060252905-A1 | Compounds containing quaternary carbons, medical devices, and methods | MEDTRONIC, INC. (US) | 2006-11-09 | — | — | US | disclosed |
| US-7101956-B2 | Compounds containing quaternary carbons, medical devices, and methods | MEDTRONIC, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| EP-1446437-A1 | COMPOUNDS CONTAINING QUATERNARY CARBONS, MEDICAL DEVICES, AND METHODS | Medtronic, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20030125499-A1 | Compounds containing quaternary carbons, medical devices, and methods | MEDTRONIC, INC. | 2003-07-03 | — | — | US | disclosed |
| WO-2003042273-A1 | COMPOUNDS CONTAINING QUATERNARY CARBONS, MEDICAL DEVICES, AND METHODS | MEDTRONIC, INC. (US) | 2003-05-22 | — | — | WO | disclosed |