Tyrosine

Tyrosine

SCHEMBL4908261

N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)[C@H](Cc1ccccc1)N(O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.69
PTGS1 P23219 3/20 0.63
ALPI P09923 1/20 0.63
PKM P14618 1/20 0.63
XIAP P98170 1/20 0.63
GRIA2 P42262 1/20 0.49
ALOX15 P16050 3/20 0.48
HIF1A Q16665 3/20 0.48
SLC1A3 P43003 2/20 0.48
SLC1A2 P43004 2/20 0.48
SLC1A1 P43005 2/20 0.48
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
USP2 O75604 1/20 0.48
EGFR P00533 1/20 0.48
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
HTR2A P28223 1/20 0.48
PTGS2 P35354 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL28481409 0.93 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL28169117 0.93 SLC7A5 (0.73) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1003558 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27641183 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL18222727 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5699039 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL133206 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28244030 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5699043 0.88 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL28263598 0.87 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166619-A1 Polypeptide connected with an organic residue MORPHOPLANT GMBH (DE) 2017-06-15 US disclosed
CN-105639210-A Eco-mark paralichthys olivaceus culture feed and application method thereof 全国水产技术推广总站 2016-06-08 CN disclosed
WO-2014128289-A1 BIOMEDICAL DEVICE IMPLANTABLE IN BONE AND/OR CARTILAGINOUS TISSUE, AND CORRESPONDING METHOD TO MANUFACTURE SAID BIOMEDICAL DEVICE LUMETTI, SIMONE (IT) 2014-08-28 WO disclosed
US-20080281069-A1 Polypeptide Connected With an Organic Residue MORPHOPLANT GMBH (DE) 2008-11-13 US disclosed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 US disclosed