Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440362 | 0.91 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL441095 | 0.82 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL438968 | 0.82 | USP30 (0.44) | DGAT1 | |
| SCHEMBL438606 | 0.81 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL4910838 | 0.79 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL4918439 | 0.79 | DGAT1 (0.45) | DGAT1 | |
| SCHEMBL437411 | 0.79 | DGAT1 (0.49) | DGAT1NTRK1 | |
| SCHEMBL440132 | 0.77 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL440674 | 0.76 | DGAT1 (0.44) | DGAT1NTRK1 | |
| SCHEMBL439873 | 0.76 | DGAT1 (0.44) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |