Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571816 | 0.87 | MAPT (0.64) | ALDH1A1MAPTNPSR1TDP1ATM | |
| SCHEMBL30585155 | 0.87 | MAPT (0.64) | ALDH1A1MAPTNPSR1TDP1ATM | |
| SCHEMBL1067105 | 0.85 | TDP1 (0.53) | ALDH1A1MAPTNPSR1TDP1ATM | |
| SCHEMBL1067110 | 0.85 | TDP1 (0.53) | ALDH1A1MAPTNPSR1TDP1ATM | |
| SCHEMBL17762761 | 0.85 | HDAC1 (0.65) | ALDH1A1MAPTHTTKMT2ALMNA | |
| SCHEMBL20560674 | 0.84 | TDP1 (0.51) | ALDH1A1MAPTNPSR1TDP1ATM | |
| SCHEMBL22535975 | 0.82 | CYP3A4 (0.55) | ALDH1A1MAPTNPSR1TDP1HTT | |
| SCHEMBL11215556 | 0.82 | NPSR1 (0.62) | ALDH1A1MAPTNPSR1TDP1HTT | |
| SCHEMBL10790188 | 0.82 | HTT (0.68) | ALDH1A1MAPTNPSR1TDP1HTT | |
| SCHEMBL8139482 | 0.82 | TDP1 (0.46) | ALDH1A1MAPTNPSR1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130863-A2 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008130863-A2 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-4801717-A | PLANT GROWTH REGULATORS | ROUSSEL UCLAF (FR) | 1989-01-31 | — | — | US | disclosed |
| EP-0119892-B1 | HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF | ROUSSEL-UCLAF (FR) | 1986-08-13 | — | — | EP | disclosed |
| US-4544400-A | HERBICIDES | ZOECON CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0119892-A1 | Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof | ROUSSEL-UCLAF (FR) | 1984-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | ABCB11, CYP2C19, HRH2 | ALDH1A1 277/4885MAPT 4338/4885NPSR1 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.