SCHEMBL490854

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16469897	0.83	CACNA1B (0.52)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL28628007	0.83	CACNA1B (0.52)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL16330581	0.83	CACNA1B (0.52)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL3735030	0.82	CTSK (0.47)	CTSKCTSSCTSLCTSBCYP1A2
	SCHEMBL3733285	0.82	CTSK (0.47)	CTSKCTSSCTSLCTSBCYP1A2
	SCHEMBL1688920	0.82	CTSK (0.47)	CTSKCTSSCTSLCTSBCYP1A2
	SCHEMBL12332835	0.82	CTSK (0.50)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL16470235	0.82	CACNA1B (0.51)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL560138	0.82	CACNA1B (0.50)	CACNA1BCTSKCTSSHDAC4HDAC1
	SCHEMBL192989	0.82	CACNA1B (0.50)	CACNA1BCTSKCTSSHDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.