Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919186 | 1.00 | TAAR1 (0.55) | TAAR1MC4RMC5RCHRM2MC3R | |
| SCHEMBL4918654 | 1.00 | TAAR1 (0.55) | TAAR1MC4RMC5RCHRM2MC3R | |
| SCHEMBL4919902 | 0.96 | TAAR1 (0.58) | TAAR1MC4RMC5RCHRM2MC3R | |
| SCHEMBL4916688 | 0.91 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMEN1 | |
| SCHEMBL4917404 | 0.91 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMEN1 | |
| SCHEMBL5034657 | 0.91 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMEN1 | |
| SCHEMBL10876835 | 0.90 | MC4R (0.57) | TAAR1MC4RMC5RCHRM2MC3R | |
| SCHEMBL4911510 | 0.89 | MEN1 (0.54) | TAAR1CHRM2IDO1KDM4EMEN1 | |
| SCHEMBL20127837 | 0.88 | TAAR1 (0.53) | TAAR1MC4RMC5RCHRM2MC3R | |
| SCHEMBL20127841 | 0.87 | CHRM2 (0.54) | TAAR1MC4RMC5RCHRM2MC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914254-B1 | Crosslinkers for improving stability of polyurethane foams | EVONIK DEGUSSA GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| US-8552078-B2 | Non-fugitive tertiary amine catalyst and alkylated polyamine crosslinking additives; aging resistance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| CN-101168601-B | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM | 2013-03-06 | — | — | CN | disclosed |
| CN-101168601-A | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20080090922-A1 | Crosslinkers for improving stability of polyurethane foams | EVONIK OPERATIONS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |