Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 2/20 | 0.54 |
| ▸ | MC5R | P33032 | 2/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919186 | 0.96 | TAAR1 (0.55) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL4918654 | 0.96 | TAAR1 (0.55) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL4908617 | 0.96 | TAAR1 (0.55) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL10876835 | 0.93 | MC4R (0.57) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL20127837 | 0.91 | TAAR1 (0.53) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL20127841 | 0.90 | CHRM2 (0.54) | TAAR1MC4RMC5RMC3RCHRM2 | |
| SCHEMBL4911510 | 0.88 | MEN1 (0.54) | TAAR1CHRM2IDO1KDM4EMAPK1 | |
| SCHEMBL5034657 | 0.86 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMAPK1 | |
| SCHEMBL4917404 | 0.86 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMAPK1 | |
| SCHEMBL4916688 | 0.86 | MEN1 (0.52) | TAAR1CHRM2IDO1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462141-B1 | NOVEL AZAHETEROCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-09-27 | — | — | EP | claimed |
| US-9023847-B2 | Azaheterocyclic compounds | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | US | claimed |
| EP-2462141-A1 | NOVEL AZAHETEROCYCLIC COMPOUNDS | Merck Patent GmbH (DE) | 2012-06-13 | — | — | EP | claimed |
| EP-3390483-B1 | ENCAPSULATION | PROCTER & GAMBLE (US) | 2022-05-18 | — | — | EP | disclosed |
| CN-107708853-B | Encapsulation | 恩盖普有限公司 | 2021-12-07 | — | — | CN | disclosed |
| EP-3368207-B1 | ENCAPSULATION | ENCAPSYS LLC (US) | 2021-12-01 | — | — | EP | disclosed |
| US-10864167-B2 | Encapsulation | THE PROCTER & GAMBLE COMPANY (US) | 2020-12-15 | — | — | US | disclosed |
| EP-3390483-A1 | ENCAPSULATION | The Procter and Gamble Company (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-3368207-A1 | ENCAPSULATION | ENCAPSYS, LLC (US) | 2018-09-05 | — | — | EP | disclosed |
| US-20180235893-A1 | ENCAPSULATION | THE PROCTER & GAMBLE COMPANY | 2018-08-23 | — | — | US | disclosed |
| US-9937477-B2 | Encapsulation | WATERTITE PRODUCTS, INC. | 2018-04-10 | — | — | US | disclosed |
| CN-101168601-B | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM | 2013-03-06 | — | — | CN | disclosed |
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | MERCK PATENT GMBH (DE) | 2012-11-01 | — | — | US | disclosed |
| CN-101168601-A | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM (US) | 2008-04-30 | — | — | CN | disclosed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| US-20080090922-A1 | Crosslinkers for improving stability of polyurethane foams | EVONIK OPERATIONS GMBH (DE) | 2008-04-17 | — | — | US | disclosed |
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277228-A1 | Novel Azaheterocyclic Compounds | PCNA, MCL1, MYC | TAAR1 3741/4885MC4R 3609/4885MC5R 3562/4885 |
| US-20180235893-A1 | ENCAPSULATION | ACR, ACMSD, SAMM50 | TAAR1 646/4885MC4R 2155/4885MC5R 3077/4885 |
| US-10864167-B2 | Encapsulation | ACR, MPHOSPH6, ACMSD | TAAR1 668/4885MC4R 2321/4885MC5R 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.