Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574833 | 0.90 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL7575682 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL28180396 | 0.87 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL1397305 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL27892763 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL4366899 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL4371967 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL21701077 | 0.84 | PLA2G1B (0.50) | ALDH1A1TDP1TSHRPLA2G1BPLA2G2A | |
| SCHEMBL27892750 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B | |
| SCHEMBL4913060 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP3A4TSHRPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914254-B1 | Crosslinkers for improving stability of polyurethane foams | EVONIK DEGUSSA GMBH (DE) | 2017-08-23 | — | — | EP | claimed |
| US-8552078-B2 | Non-fugitive tertiary amine catalyst and alkylated polyamine crosslinking additives; aging resistance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-10-08 | — | — | US | claimed |
| CN-101168601-B | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM | 2013-03-06 | — | — | CN | claimed |
| EP-1914254-A1 | Crosslinkers for improving stability of polyurethane foams | Air Products and Chemicals, Inc. (US) | 2008-04-23 | — | — | EP | claimed |
| US-20080090922-A1 | Crosslinkers for improving stability of polyurethane foams | EVONIK OPERATIONS GMBH (DE) | 2008-04-17 | — | — | US | claimed |
| CN-101168601-B | Crosslinkers for improving stability of polyurethane foams | AIR PROD & CHEM | 2013-03-06 | — | — | CN | disclosed |