Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 20/20 | 0.47 |
| ▸ | CA1 | P00915 | 20/20 | 0.47 |
| ▸ | CA2 | P00918 | 20/20 | 0.47 |
| ▸ | CA4 | P22748 | 20/20 | 0.47 |
| ▸ | CA7 | P43166 | 20/20 | 0.47 |
| ▸ | CA9 | Q16790 | 20/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780968 | 0.93 | CA12 (0.49) | CA12CA1CA2CA4CA7 | |
| SCHEMBL14196276 | 0.84 | HRH4 (0.46) | — | |
| SCHEMBL14223014 | 0.84 | HRH4 (0.46) | — | |
| SCHEMBL14222473 | 0.84 | HRH4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL4795755 | 0.83 | HRH4 (0.45) | — | |
| SCHEMBL1749349 | 0.82 | CA12 (0.53) | CA12CA1CA2CA4CA7 | |
| SCHEMBL14196277 | 0.80 | PDE10A (0.48) | CA12CA1CA2CA4CA7 | |
| SCHEMBL4885872 | 0.79 | HRH4 (0.49) | CA12CA1CA2CA4CA7 | |
| SCHEMBL15205294 | 0.78 | TRPV1 (0.50) | CA12CA1CA2CA4CA7 | |
| SCHEMBL997974 | 0.78 | TRPV1 (0.50) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041090-A1 | MALANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONIST PYRIDINONES | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |