Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 15/20 | 0.49 |
| ▸ | CA1 | P00915 | 15/20 | 0.49 |
| ▸ | CA2 | P00918 | 15/20 | 0.49 |
| ▸ | CA4 | P22748 | 15/20 | 0.49 |
| ▸ | CA7 | P43166 | 15/20 | 0.49 |
| ▸ | CA9 | Q16790 | 15/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15206576 | 1.00 | TRPV1 (0.50) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL15205294 | 1.00 | TRPV1 (0.50) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL31140038 | 0.92 | AKR1C3 (0.50) | TRPV1TRPM8AKR1C3 | |
| SCHEMBL1728874 | 0.92 | AKR1C3 (0.50) | TRPV1TRPM8AKR1C3 | |
| SCHEMBL15205421 | 0.88 | TRPV1 (0.49) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL15206064 | 0.88 | TRPV1 (0.49) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL1749349 | 0.85 | CA12 (0.53) | TRPV1CA12CA1CA2CA4 | |
| SCHEMBL391173 | 0.85 | TRPV1 (0.52) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL392349 | 0.85 | TRPV1 (0.54) | TRPV1TRPM8CA12CA1CA2 | |
| SCHEMBL392348 | 0.85 | TRPV1 (0.54) | TRPV1TRPM8CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867980-B2 | Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184746-A1 | LINCOSAMIDE DERIVATIVES AND ANTIMICROBIAL AGENTS COMPRISING THE SAME AS ACTIVE INGREDIENT | SIRT6, LAS1L, MRPS18A | TRPV1 616/4885TRPM8 675/4885CA12 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.