Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906241 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BTGM2HDAC1HDAC8 | |
| SCHEMBL6389169 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BTGM2HDAC1HDAC8 | |
| SCHEMBL4911413 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BTGM2HDAC1HDAC8 | |
| SCHEMBL6809191 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BHDAC1HDAC8TSHR | |
| SCHEMBL6809187 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BHDAC1HDAC8TSHR | |
| SCHEMBL8361164 | 0.79 | DPP7 (0.40) | — | |
| SCHEMBL24485007 | 0.78 | HRH2 (0.43) | ITGB3ITGA2BHDAC8CTSKTSHR | |
| SCHEMBL6809194 | 0.78 | TSHR (0.41) | ITGB3ITGA2BCTSKTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL4910467 | 0.78 | DPP7 (0.39) | — | |
| SCHEMBL6392307 | 0.74 | ITGB3 (0.55) | ITGB3ITGA2BTGM2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | FERRING B.V. | 2008-10-16 | — | — | US | disclosed |
| US-7335677-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2008-02-26 | — | — | US | disclosed |
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | FERRING B. V. | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043299-A1 | Inhibitors of dipeptidyl peptidase iv | DPP4, DPP9, DPP3 | ITGB3 4014/4885ITGA2B 3782/4885TGM2 293/4885 |
| US-20080255126-A1 | Inhibitors of post-proline cleaving proteases | PREP, PEPD, DPP4 | ITGB3 4250/4885ITGA2B 4214/4885TGM2 440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.