Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908833 | 1.00 | TSHR (0.56) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4909965 | 1.00 | TSHR (0.56) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7045171 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9168790 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3278460 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17817108 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7045133 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7043129 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1608893 | 0.87 | TSHR (0.57) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23014013 | 0.86 | MAPT (0.74) | TSHRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269458-A1 | POLYIMIDE AND LIQUID CRYSTAL ALIGNMENT FILM THEREOF | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269458-A1 | POLYIMIDE AND LIQUID CRYSTAL ALIGNMENT FILM THEREOF | PUF60, DDT, PARG | TSHR 4533/4885MAPT 89/4885ALDH1A1 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.