Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278460 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL7045171 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL1608893 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL17817108 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL7045133 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL9168790 | 1.00 | TSHR (0.57) | TSHRMAPTGAAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11836521 | 0.96 | GAA (0.61) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL11747860 | 0.95 | GAA (0.60) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL7056177 | 0.92 | GAA (0.59) | TSHRMAPTGAAALDH1A1KDM4E | |
| SCHEMBL7750765 | 0.92 | TSHR (0.50) | TSHRMAPTGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054049-B1 | Optical compensators | CHISSO CORP (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-1054049-A1 | Optical compensators | CHISSO CORPORATION (JP) | 2000-11-22 | — | — | EP | disclosed |
| US-5453220-A | Calixarene-based transition metal complexes and photonic devices comprising the same | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-09-26 | — | — | US | disclosed |