Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675744 | 0.87 | HSD17B1 (0.60) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL32677328 | 0.85 | APP (0.81) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL27159530 | 0.85 | APP (0.81) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL28357616 | 0.84 | APP (0.69) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL4909636 | 0.83 | APP (0.62) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL13766429 | 0.83 | APP (0.62) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL16021770 | 0.82 | APP (0.47) | APPHSD17B1HSD17B2CA1CA2 | |
| Alcohol SCHEMBL28260373 | 0.81 | APP (0.64) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL6172601 | 0.80 | APP (1.00) | APPHSD17B1HSD17B2CA1CA2 | |
| SCHEMBL23555697 | 0.80 | APP (0.72) | APPHSD17B1HSD17B2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299041-A1 | HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299041-A1 | HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION | APP, BACE1, PSEN1 | APP 1/4885HSD17B1 483/4885HSD17B2 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.