Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.72 |
| ▸ | PDE2A | O00408 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914691 | 0.88 | RORC (0.56) | RORCPDE2ATSHRUSP2ALDH1A1 | |
| SCHEMBL4915106 | 0.86 | RORC (0.68) | RORCPDE2ATSHRUSP2ALDH1A1 | |
| SCHEMBL2034981 | 0.84 | RORC (0.80) | RORCTSHRUSP2ALDH1A1GAA | |
| SCHEMBL29393026 | 0.84 | RORC (1.00) | RORCTSHRUSP2ALDH1A1GAA | |
| SCHEMBL125246 | 0.84 | RORC (1.00) | RORCTSHRUSP2ALDH1A1GAA | |
| SCHEMBL29492951 | 0.84 | RORC (1.00) | RORCTSHRUSP2ALDH1A1GAA | |
| SCHEMBL4905932 | 0.83 | PDE2A (0.49) | RORCPDE2AALDH1A1HPGDALOX15 | |
| SCHEMBL9861928 | 0.83 | RORC (0.51) | RORCPDE2AESR1ESR2 | |
| SCHEMBL24180098 | 0.82 | PDE2A (0.54) | RORCPDE2ATSHRDPP7HTR2A | |
| SCHEMBL2759875 | 0.82 | RORC (0.49) | RORCPDE2ATSHRDPP7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | BAKER MAX T | 2008-12-18 | — | — | US | disclosed |
| US-7312250-B2 | Fluorine-substituted alkyl phenol compounds and their uses | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2003077894-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | IOWA RESEARCH FOUNDATION, UNIVERSITY OF | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176513-A1 | Fluorine-substituted alkyl phenol compounds and their uses | AFF4, AFF1, AFF2 | RORC 278/4885PDE2A 1999/4885TSHR 1138/4885 |
| US-20080312339-A1 | FLUORINE-SUBSTITUTED ALKYL PHENOL COMPOUNDS AND THEIR USES | AFF4, AFF1, AFF2 | RORC 278/4885PDE2A 1999/4885TSHR 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.