Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913183 | 0.83 | DHFR (0.38) | DHFRIDO1SMN1; SMN2AGXTTSHR | |
| SCHEMBL4912485 | 0.69 | MAOB (0.41) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4914488 | 0.69 | IDO1 (0.39) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4912652 | 0.68 | IDO1 (0.42) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4911548 | 0.66 | IDO1 (0.48) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4955620 | 0.66 | IDO1 (0.36) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4952930 | 0.66 | ROCK1 (0.39) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4913854 | 0.66 | MAOB (0.41) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4914000 | 0.66 | IDO1 (0.39) | DHFRALDH1A1IDO1SMN1; SMN2AGXT | |
| SCHEMBL4911096 | 0.66 | DHFR (0.40) | DHFRALDH1A1IDO1SMN1; SMN2AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | claimed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | claimed |
| US-7399317-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-15 | — | — | US | disclosed |
| US-20080092306-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-04-24 | — | — | US | disclosed |
| EP-1781241-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2007-03-08 | — | — | US | disclosed |
| WO-2006026488-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070050922-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, NOX5 | DHFR 164/4885ALDH1A1 420/4885IDO1 1934/4885 |
| US-20080092306-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, KDM5A, NOX5 | DHFR 164/4885ALDH1A1 420/4885IDO1 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.