Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938485 | 0.85 | TACR1 (0.86) | TACR1CCR3 | |
| SCHEMBL7932634 | 0.85 | TACR1 (1.00) | TACR1CCR3 | |
| SCHEMBL6712492 | 0.82 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840886 | 0.81 | CCR3 (1.00) | CCR3 | |
| SCHEMBL7936410 | 0.80 | TACR1 (1.00) | TACR1CCR3 | |
| SCHEMBL7934599 | 0.78 | TACR1 (1.00) | TACR1CCR3 | |
| SCHEMBL7934798 | 0.78 | TACR1 (1.00) | TACR1 | |
| SCHEMBL18840797 | 0.78 | CCR3 (1.00) | CCR3 | |
| SCHEMBL18840874 | 0.77 | CCR3 (1.00) | TACR1CCR3 | |
| SCHEMBL18840843 | 0.76 | CCR3 (1.00) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171749-A1 | 1-Phenyl-1,2-Diaminoethane Derivatives As Modulators Of The Chemokine Receptor Activity | DOLLINGER HORST | 2008-07-17 | — | — | US | disclosed |
| US-20040063779-A1 | 1-Phenyl-1,2-diaminoethane derivatives as modulators of the chemokine receptor activity | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171749-A1 | 1-Phenyl-1,2-Diaminoethane Derivatives As Modulators Of The Chemokine Receptor Activity | CCR1, CCR3, CCR2 | TACR1 143/4885CCR3 2/4885 |
| US-20040063779-A1 | 1-Phenyl-1,2-diaminoethane derivatives as modulators of the chemokine receptor activity | CCR1, CCR3, CCR2 | TACR1 69/4885CCR3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.