SCHEMBL491197

SCHEMBL491197

COC(=O)CCC(C)(C#N)N=NC(C)(C#N)CCC(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
HPGD P15428 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3225387 1.00 TSHR (0.43) TSHRKMT2AMEN1LMNAALDH1A1
SCHEMBL15759062 0.93 TSHR (0.43) TSHRKMT2AMEN1LMNAALDH1A1
SCHEMBL15355937 0.87 TSHR (0.41) TSHRKMT2AMEN1LMNAALDH1A1
SCHEMBL11648921 0.82
SCHEMBL11648924 0.82
SCHEMBL10016885 0.82 DGKA (0.33) TSHRMAPT
SCHEMBL14649851 0.81
SCHEMBL14085157 0.81 TSHR (0.36) TSHRALDH1A1KDM4ERECQLHSD17B10
SCHEMBL9155844 0.81
SCHEMBL9155838 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090142692-A1 LOW MOLECULAR WEIGHT LATEX AND TONER COMPOSITIONS COMPRISING THE SAME XEROX CORPORATION (US) 2009-06-04 US claimed
US-20060286476-A1 manufactured under monomer-starved polymerization condition such as monomer feeding rate equal to or less than 0.516% per minute by weight of the monomer(s) to be fed; gloss, fusing performance, crease performance, stripping performance, document offset, vinyl offset, and parent charging etc. XEROX CORPORATION 2006-12-21 US claimed
US-5506320-A A SATURATED POLYMERIC BACKBONE HAVING REACTIVE GROUPS AT EACH END AND AT LEAST ONE PENDANT CHAIN WHICH IS MISCIBLE WITH THE THERMOSETTING RESIN WHILE IT IS UNCURED THE B. F. GOODRICH COMPANY (US) 1996-04-09 US claimed
EP-3608367-B1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION AND BASE MATERIAL SHINETSU CHEMICAL CO (JP) 2024-07-10 EP disclosed
US-20240153687-A1 COMPOSITION HAVING MAGNETOSTRICTIVE PROPERTIES, AND CURED PRODUCT THEREOF TOHOKU UNIVERSITY (JP) 2024-05-09 US disclosed
EP-3594220-B1 ORGANOSILICON COMPOUND AND METHOD FOR PRODUCING SAME SHINETSU CHEMICAL CO (JP) 2024-05-08 EP disclosed
EP-4303244-A1 COMPOSITION HAVING MAGNETOSTRICTIVE PROPERTIES, AND CURED PRODUCT THEREOF TOKYO OHKA KOGYO CO., LTD. (JP) 2024-01-10 EP disclosed
EP-3783037-B1 POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR SHINETSU CHEMICAL CO (JP) 2024-01-10 EP disclosed
WO-2023214526-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME 信越化学工業株式会社 2023-11-09 WO disclosed
CN-111989348-B Polymer having reactive silicon-containing group and method for producing same 信越化学工业株式会社 2023-10-20 CN disclosed
CN-111989333-B Organosilicon compound and method for producing same 信越化学工业株式会社 2023-09-15 CN disclosed
US-6607864-B2 Heating heating member that is in contact with a toner image to fix toner image onto a recording medium, wherein a surface of heating member or vicinity generates heat, and a toner forming the toner image contains a colorant and binder resin FUJI XEROX CO., LTD. (JP) 2003-08-19 US disclosed
US-20030027073-A1 Image forming method FUJI XEROX CO., LTD. (JP) 2003-02-06 US disclosed
US-5506320-A A SATURATED POLYMERIC BACKBONE HAVING REACTIVE GROUPS AT EACH END AND AT LEAST ONE PENDANT CHAIN WHICH IS MISCIBLE WITH THE THERMOSETTING RESIN WHILE IT IS UNCURED THE B. F. GOODRICH COMPANY (US) 1996-04-09 US disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
US-4359542-A PREPARATION OF FOAMS OLIN CORPORATION (US) 1982-11-16 US disclosed
US-4258148-A FREE RADICAL INITIATION OLIN CORPORATION (US) 1981-03-24 US disclosed
US-4094868-A Azo di-ester polyols for graft copolymerization OLIN CORPORATION (US) 1978-06-13 US disclosed