Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 10/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732396 | 0.94 | SLC6A4 (0.58) | SLC6A4HRH3SLC6A9HTR1A | |
| SCHEMBL4919787 | 0.93 | SLC6A4 (0.59) | SLC6A4HRH3SLC6A9 | |
| Trifluoroacetic Acid SCHEMBL4925697 | 0.87 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A9UTS2R | |
| Trifluoroacetic Acid SCHEMBL4924285 | 0.86 | SLC6A4 (0.69) | SLC6A4HRH3SLC6A9PPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL4916562 | 0.85 | HRH3 (0.58) | SLC6A4HRH3SLC6A9PPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL4919069 | 0.85 | SLC6A4 (0.60) | SLC6A4HRH3SLC6A9HTR1A | |
| SCHEMBL4736298 | 0.83 | SLC6A4 (0.55) | SLC6A4HRH3 | |
| SCHEMBL4921696 | 0.83 | SLC6A4 (0.75) | SLC6A4HRH3SLC6A9UTS2R | |
| SCHEMBL4921656 | 0.82 | SLC6A4 (0.73) | SLC6A4HRH3SLC6A9UTS2R | |
| SCHEMBL4784335 | 0.80 | SLC6A4 (0.69) | SLC6A4HRH3SLC6A9HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | SLC6A4 2/4885HRH3 1/4885SLC6A9 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.