SCHEMBL4911975

SCHEMBL4911975

Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N(c2ccccc2)C2C3CCC(C3)C2CO)cc1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813499 0.82 BDKRB1 (0.60) BDKRB1
SCHEMBL4179678 0.79 BDKRB1 (0.71) BDKRB1
SCHEMBL3533258 0.75 BDKRB1 (0.67) BDKRB1
SCHEMBL3533254 0.75 BDKRB1 (0.67) BDKRB1
SCHEMBL5532948 0.74 BDKRB1 (0.58) BDKRB1
SCHEMBL4819558 0.74 BDKRB1 (0.53) BDKRB1
SCHEMBL4180744 0.73 BDKRB1 (0.70) BDKRB1
SCHEMBL4172651 0.73 BDKRB1 (0.70) BDKRB1
SCHEMBL4174798 0.72 BDKRB1 (0.68) BDKRB1
SCHEMBL4174794 0.72 BDKRB1 (0.68) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963285-A1 BRADYKININ 1 RECEPTOR ANTAGONISTS Amgen Inc. (US) 2008-09-03 EP claimed
WO-2007067629-A1 BRADYKININ 1 RECEPTOR ANTAGONISTS AMGEN INC. (US) 2007-06-14 WO claimed