Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843978 | 0.86 | MAPT (0.74) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL391385 | 0.86 | MAPT (0.74) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL3842527 | 0.86 | MAPT (0.74) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL83814 | 0.86 | TEAD4 (0.74) | ALDH1A1MAPTTEAD4TDP1POLB | |
| SCHEMBL95343 | 0.86 | TEAD4 (0.74) | ALDH1A1MAPTTEAD4TDP1POLB | |
| SCHEMBL83863 | 0.86 | TEAD4 (0.74) | ALDH1A1MAPTTEAD4TDP1POLB | |
| SCHEMBL10892248 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTTEAD4TDP1POLB | |
| SCHEMBL29377968 | 0.83 | TEAD4 (0.70) | ALDH1A1MAPTTEAD4TDP1POLB | |
| Phosphine SCHEMBL22361928 | 0.83 | TEAD4 (0.70) | ALDH1A1MAPTTEAD4TDP1POLB | |
| Phosphine SCHEMBL23732402 | 0.83 | MAPT (0.70) | ALDH1A1MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360156-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-10-31 | — | — | US | disclosed |
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-08-10 | — | — | US | disclosed |
| US-11279713-B2 | Heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-03-22 | — | — | US | disclosed |
| EP-3778588-A1 | QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| US-20200317692-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-10-08 | — | — | US | disclosed |
| US-10654874-B2 | Heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-05-19 | — | — | US | disclosed |
| EP-2603513-B1 | HETEROCYCLIC COMPOUND AND USE THEREOF AS AMPA RECEPTOR POSITIVE ALLOSTERIC MODULATOR | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| WO-2019185046-A1 | QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF | 上海美悦生物科技发展有限公司 | 2019-10-03 | — | — | WO | disclosed |
| US-20190263832-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-08-29 | — | — | US | disclosed |
| US-20180162875-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-14 | — | — | US | disclosed |
| EP-0654492-A2 | Degradable aliphatic polyester formed products | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5401796-A | Aliphatic polyester and preparation process thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0618249-A2 | Aliphatic polyester and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5310865-A | Polyhydroxycarboxylic acid and preparation process thereof | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0572675-A1 | POLYHYDROXY CARBOXYLIC ACID AND PRODUCTION THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4564712-A | Process for the preparation of diphenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |
| US-4098908-A | PHENOXYPHENYL PYRIDYL KETONES AND DERIVATIVES AND THEIR USE AS HYPOLEPIDEMIC AGENTS | SANDOZ, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
| US-4031233-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3939113-A | ANTHRAQUINONE DYES | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263832-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-20200317692-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-20240360156-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-20180162875-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-10654874-B2 | Heterocyclic compound and use thereof | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-11279713-B2 | Heterocyclic compound and use thereof | GRIN1, GRIN2C, GRIN2A | ALDH1A1 177/4885MAPT 277/4885TEAD4 1466/4885 |
| US-20230248833-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | BTK, WEE1, WEE2 | ALDH1A1 3737/4885MAPT 4619/4885TEAD4 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.